Product Name: EGFR antibody [SP9]
Applications: FACS, IHC, IHC-P, WB
Predicted Target Size:
Positive Controls: Placenta and lung
Form Supplied:
Concentration:
Purification: Tissue culture supernatant
Full Name: epidermal growth factor receptor
Background: Epidermal Growth factor receptor (EGFR) is the prototype member of the type 1 receptor tyrosine kinases. EGFR is encoded by the cellular oncogene cerbB1. EGFR has an extracellular ligand binding domain, a single transmembrane region, and cytoplasmic domain which is composed of a tyrosine kinase domain and a carboxy terminal domain. The carboxy terminal domain contains at least four tyrosine autophosphorylation sites. EGFR over expression in tumors indicates poor prognosis. EGFR over expression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.
Synonyms: ERBB1, 131550, 1956, EGFR, ERBB, mENA, P00533
Cellular Localization: Cell Membrane and Secreted
CAS NO: 144598-75-4
Product: Poloxin
Host: Rabbit
Clonality: Monoclonal
Isotype:
Immunogen: Synthetic peptide (Human) (C terminal).
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Preservative: 0.1% Sodium Azide
Storage Instruction: Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24288375?dopt=Abstract
