Product Name: EIF3A antibody [N1N2], N-term
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 167 kDa (note) (2)
Positive Controls: Raji
Form Supplied: Liquid
Concentration: 0.96 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: eukaryotic translation initiation factor 3, subunit A
Background: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of posttermination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation.
Synonyms: EIF3 antibody, EIF3S10 antibody, KIAA0139 antibody, P167 antibody, TIF32 antibody, eIF3-p170 antibody, eIF3-theta antibody, p180 antibody, p185 antibody, EIF3A antibody, “eukaryotic translation initiation factor 3, subunit 10 (theta, 170kD) antibody”, “eukaryotic translation initiation factor 3, subunit 10, 170kD antibody”, “eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa antibody”, “EIF3, p180 subunit antibody”, eukaryotic translation initiation factor 3 subunit 10 antibody, “eukaryotic translation initiation factor 3, subunit 10 (theta, 150/170kD) antibody”, centrosomin homolog antibody, eukaryotic translation initiation factor 3 subunit A antibody, eIF-3-theta antibody, eIF3 p185 antibody, eIF3 p180 antibody, eIF3 p167 antibody, cytoplasmic protein p167 antibody, “eukaryotic translation initiation factor 3, subunit A antibody”
Cellular Localization: Cytoplasm
CAS NO: 717906-29-1
Product: Elesclomol
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human EIF3A. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21411642?dopt=Abstract
