Product Name: ELMO1 antibody, C-term
Applications: IP, WB
Predicted Target Size:
Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX89955-PEP).
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: engulfment and cell motility 1
Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Synonyms: engulfment and cell motility1, engulfment and cell motility 1 (ced12 homolog, C. elegans), MGC126406, CED12, OTTHUMP00000207060, ced12 homolog1, engulfment and cell motility 1, engulfment and cell motility 1 (ced-12 homolog, C. elegans), ELMO-1, ced-12 homolog 1, ced12 homo, engulfment and cell motility1 (ced12 homolog, C. elegans), CED-12, KIAA0281, ELMO1, ELMO 1, CED 12, ced 12 homolog 1, ced12 homolog 1
Cellular Localization: Translocation to plasma membrane seems to be mediated by DOCK1 and CRK.
CAS NO: 36085-73-1
Product: Sulindac
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: PKEPSNYDFVYDCN
Antigen Species: Human
Species Reactivity: Human, Zebrafish, Bovine
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for ELMO1.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27440880?dopt=Abstract
