Product Name: ELMO2 antibody, C-term
Applications: IHC-P, WB
Predicted Target Size:
Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX89956-PEP).
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: engulfment and cell motility 2
Background: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.
Synonyms: RP11394O2.2, ELMO2, FLJ11656, engulfment and cell motility2, CED12, RP11-394O2.2, ced-12 homolog 2, engulfment and cell motility 2, engulfment and cell motility 2 (ced-12 homolog, C. elegans), PH domain protein CED12A, ced12 homolog2, engulfment and cell motility2 (ced12 homolog, C. elegans), CED-12, ced12 homolog 2, KIAA1834, engulfment, ELMO-2, CED 12, ELMO 2, ced 12 homolog 2
Cellular Localization:
CAS NO: 851983-85-2
Product: JTC-801
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: C-PKEPSSYDFVYHYG
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for ELMO2.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27623537?dopt=Abstract
