Product Name: ENPP3 antibody [NP4D6] (PE-Dyomics 647)
Applications: FACS, ICC/IF
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification:
Full Name: ectonucleotide pyrophosphatase/phosphodiesterase 3
Background: CD203c, also known as ENPP-3, is integral membrane ectoenzyme (ectonucleotide pyrophosphatase/phosphodiesterase 3), that hydrolyses nucleotide triphosphates and thus modulates purinergic signaling. CD203c is expressed mainly on activated basophils and mast cells. CD203c is upregulated in response to IgE-receptor cross-linking and is overexpressed on neoplastic mast cells in patients with systemic mastocytosis. Measurement of its induced enhancement on the plasma membrane is useful for diagnostics of allergies.Entrez Gene: 5169
Synonyms: B10, CD203c, NPP3, PD-IBETA, PDNP3
Cellular Localization: Located to the apical surface in intestinal and kidney epithelial cells. Located to the cell surface of basophils, and to the apical plasma membrane of bile duct cells. Secreted in serum, and in lumen of epithelial cells.
CAS NO: 468740-43-4
Product: Toll-like receptor modulator
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: HEK-293 cells transfected with human ENPP3.
Antigen Species: Human
Species Reactivity: Human
Conjugation: PE-Dyomics 647
Storage Buffer: The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Storage Instruction: Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.Do not use after expiration date stamped on vial label. Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is sto
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: The mouse monoclonal antibody NP4D6 reacts with ENPP3, a transmembrane ectoenzyme expressed on basophils and mast cells, and overexpressed upon their activation.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25799239?dopt=Abstract
