Product Name: EP300 antibody
Applications: IHC, IHC-P, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The antibody was purified by immunogen affinity chromatography.
Full Name: E1A binding protein p300
Background: This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
Synonyms: p300 Antibody , KAT3B Antibody , RSTS2 Antibody , E1A binding protein p300 Antibody
Cellular Localization:
CAS NO: 1029044-16-3
Product: TG101209
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the N-term region of human p300. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse, Chicken, Dog, Pig, Rat, Bovine
Conjugation: Unconjugated
Storage Buffer: Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.
Storage Instruction: Shipped at 4 C. Upon delivery aliquot and store at -20 C for one year. Avoid freeze/thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Recognizes endogenous levels of p300 protein.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24618807?dopt=Abstract
