Product Name: EPC1 antibody
Applications: WB
Predicted Target Size:
Positive Controls: Recombinant protein
Form Supplied: Liquid
Concentration:
Purification: Unpurified
Full Name: enhancer of polycomb homolog 1 (Drosophila)
Background: Component of the NuA4 histone acetyltransferase (HAT) complex which is involved in transcriptional activation of select genes principally by acetylation of nucleosomal histones H4 and H2A. This modification may both alter nucleosome – DNA interactions and promote interaction of the modified histones with other proteins which positively regulate transcription. This complex may be required for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis, and DNA repair. NuA4 may also play a direct role in DNA repair when directly recruited to sites of DNA damage.
Synonyms: DKFZp781P2312, Epl1
Cellular Localization:
CAS NO: 1186206-79-0
Product: VX-702
Host: Mouse
Clonality: Polyclonal
Isotype:
Immunogen: EPC1 (NP_079485, 695 a.a. ~ 799 a.a) partial recombinant protein with GST tag.
Antigen Species: Human
Species Reactivity: Human, Cat
Conjugation: Unconjugated
Storage Buffer: Antiserum containing 50% glycerol
Storage Instruction: Upon Receipt – Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Not tested
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25205765?dopt=Abstract
