Product Name: ERAB antibody [N2C3]
Applications: IHC-P, WB
Predicted Target Size: 27 kDa (note) (3)
Positive Controls: 293T , HeLa , HepG2 , Molt-4 , Raji
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: hydroxysteroid (17-beta) dehydrogenase 10
Background: This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimers disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq]
Synonyms: 17b-HSD10 antibody, ABAD antibody, CAMR antibody, DUPXp11.22 antibody, ERAB antibody, HADH2 antibody, HCD2 antibody, MHBD antibody, MRPP2 antibody, MRX17 antibody, MRX31 antibody, MRXS10 antibody, SCHAD antibody, SDR5C1 antibody, HSD17B10 antibody, endoplasmic reticulum-associated amyloid beta-peptide-binding protein antibody, short chain type dehydrogenase/reductase XH98G2 antibody, AB-binding alcohol dehydrogenase antibody, mitochondrial ribonuclease P protein 2 antibody, 3-hydroxyacyl-CoA dehydrogenase type-2 antibody, short chain L-3-hydroxyacyl-CoA dehydrogenase type 2 antibody, 3-hydroxy-2-methylbutyryl-CoA dehydrogenase antibody, “short chain dehydrogenase/reductase family 5C, member 1 antibody”, amyloid-beta peptide binding alcohol dehydrogenase antibody, hydroxysteroid (17-beta) dehydrogenase 10 antibody
Cellular Localization: Mitochondrion
CAS NO: 957054-30-7
Product: WZ-3146
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human ERAB. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24895528?dopt=Abstract
