Product Name: ERCC1 antibody [8F1]
Applications: IHC, IHC-Fr, IHC-P, IP, WB
Predicted Target Size:
Positive Controls: Tonsil.
Form Supplied: Liquid
Concentration: 0.1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: IgG fraction
Full Name: excision repair cross-complementing rodent repair deficiency, complementation group 1 (includes overlapping antisense sequence)
Background: ERCC1 is required for nucleotide excision repair of damaged DNA and is homologous to RAD10. In mammalian cells, XPG cleaves 3 of the DNA lesion while ERCC1-XPF complex makes the 5 incision.
Synonyms: 126380, 2067, P07992, UV20, ERCC1
Cellular Localization: Nuclear
CAS NO: 53179-13-8
Exatecan (Mesylate)
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2b
Immunogen: Recombinant full length protein
Antigen Species: Human
Species Reactivity: Human, Rat
Conjugation: Unconjugated
Storage Buffer: Phosphate-buffered saline, pH 7.2, containing 0.05% sodium azide
Storage Instruction: Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody reacts with a 33-36 kD protein known as ERCC1 (Excision Repair Cross Complementing) polypeptide.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21152024?dopt=Abstract
