Product Name: E-Cadherin antibody [67A4] (APC)
Applications: FACS, ICC/IF, IHC-Fr, IP, WB
Predicted Target Size:
Positive Controls:
Form Supplied:
Concentration:
Purification:
Full Name: cadherin 1, type 1, E-cadherin (epithelial)
Background: CD324 / E-cadherin is an epithelial cell surface molecule, which provides calcium-dependent homophilic interactions with E-cadherin of another cell. These intaractions take part in morphogenetic programs controlling the maintenance of the structural and functional integrity of epithelia and affect invasive potential of epithelial neoplasms. CD324 / E-cadherin is implicated in cell growth and differentiation, cell recognition, and sorting during developmental morphogenesis, as well as in aggregation-dependent cell survival. CD324 / E-cadherin-mediated cell adhesion system is highly regulated from inside the cell by a number of intracellular signaling pathways.Entrez Gene (human): 16q22.1
Synonyms: Arc-1, CDHE, ECAD, LCAM, UVO, E-Cadherin
Cellular Localization: Colocalizes with DLGAP5 at sites of cell-cell contact in intestinal epithelial cells. Anchored to actin microfilaments through association with alpha-, beta- and gamma-catenin. Sequential proteolysis induced by apoptosis or calcium influx, results in tran
CAS NO: 944396-07-0
Product: (R)-5-Hydroxymethyl Tolterodine
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: T-47D cells
Antigen Species: Human
Species Reactivity: Human
Conjugation: Allophycocyanin (APC)
Storage Buffer: The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2% (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Storage Instruction: Store in the dark at 2-8°C. Do not freeze. Avoid prolonged exposure to light.Do not use after expiration date stamped on vial label. Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is sto
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: The mouse monoclonal antibody 67A4 recognizes CD324 / E-cadherin, an approximately 100 kDa epithelial cell adhesion molecule, whose detection is important for determination of invasive potential of epithelial neoplasms.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24501276?dopt=Abstract
