Product Name: Elongin A antibody [C2C3], C-term
Applications: WB
Predicted Target Size: 90 kDa (note) (2)
Positive Controls: A549 , HeLa
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A)
Background: This gene encodes the protein elongin A, which is a subunit of the transcription factor B (SIII) complex. The SIII complex is composed of elongins A/A2, B and C. It activates elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites within transcription units. Elongin A functions as the transcriptionally active component of the SIII complex, whereas elongins B and C are regulatory subunits. Elongin A2 is specifically expressed in the testis, and capable of forming a stable complex with elongins B and C. The von Hippel-Lindau tumor suppressor protein binds to elongins B and C, and thereby inhibits transcription elongation. [provided by RefSeq]
Synonyms: EloA antibody, FLJ38760 antibody, FLJ42849 antibody, SIII antibody, SIII p110 antibody, TCEB3A antibody, TCEB3 antibody, transcription elongation factor B alpha subunit antibody, elongin-A antibody, transcription elongation factor B polypeptide 3 antibody, elongin 110 kDa subunit antibody, RNA polymerase II transcription factor SIII subunit A1 antibody, “transcription elongation factor B (SIII), polypeptide 3 (110kDa, elongin A) antibody”
Cellular Localization:
CAS NO: 802539-81-7
Product: BAN ORL 24
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Elongin A. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26040698?dopt=Abstract
