Product Name: Endothelin 1 antibody [TR.ET.48.5]
Applications: Blocking, ELISA, FACS, ICC/IF, IHC, IHC-Fr, IHC-P, IP, RIA, WB
Predicted Target Size: 24 kDa (note)
Positive Controls:
Form Supplied: Liquid
Concentration: 2.50 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity chromatography
Full Name: endothelin 1
Background: The protein encoded by this gene is proteolytically processed to release a secreted peptide termed endothelin 1. This peptide is a potent vasoconstrictor and is produced by vascular endothelial cells. Endothelin 1 also can affect the central nervous system. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2009]
Synonyms: ET1 Antibody , EDN1 Antibody , endothelin 1 Antibody , HDLCQ7 Antibody , PPET1 Antibody
Cellular Localization:
CAS NO: 215543-92-3
Product: AMD-070
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: The immunogen corresponding to a region within amino acids 60 and 68 of human ET-1 (Uniprot: P05305).
Antigen Species: Human
Species Reactivity: Human, Mouse, Dog, Pig, Rat, Rabbit, Sheep, Sheep
Conjugation: Unconjugated
Storage Buffer: PBS containing 0.05 % sodium azide
Storage Instruction: -20° C, Avoid Freeze/Thaw Cycles
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody shows little cross-reactivity to related peptides and no known cross-reactivity to non-related peptides. This antibody is not recommended for human placenta tissue or HepG2 cells in Western blot applications.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27083515?dopt=Abstract