Product Name: EpCAM antibody [N3C3]
Applications: IHC-P, WB
Predicted Target Size: 35 kDa (note)
Positive Controls: H1299 , HCT116 , MCF-7 , Molt-4
Form Supplied: Liquid
Concentration: 0.81 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: epithelial cell adhesion molecule
Background: This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq]
Synonyms: DIAR5 antibody, EGP-2 antibody, EGP314 antibody, EGP40 antibody, ESA antibody, GA733-2 antibody, HNPCC8 antibody, KS1/4 antibody, KSA antibody, M4S1 antibody, MIC18 antibody, MK-1 antibody, TACSTD1 antibody, TROP1 antibody, EPCAM antibody, major gastrointestinal tumor-associated protein GA733-2 antibody, epithelial glycoprotein 314 antibody, human epithelial glycoprotein-2 antibody, tumor-associated calcium signal transducer 1 antibody, “membrane component, chromosome 4, surface marker (35kD glycoprotein) antibody”, adenocarcinoma-associated antigen antibody, epithelial cell adhesion molecule antibody, cell surface glycoprotein Trop-1 antibody
Cellular Localization: Membrane; Single-pass type I membrane protein
CAS NO: 1269440-17-6
Product: PCI-24781
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human EpCAM. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23858059?dopt=Abstract