Product Name: EpCAM antibody [N/A]
Applications: IHC-P
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Ab purified by Protein A
Full Name: epithelial cell adhesion molecule
Background: This gene encodes a carcinoma-associated antigen and is a member of a family that includes at least two type I membrane proteins. This antigen is expressed on most normal epithelial cells and gastrointestinal carcinomas and functions as a homotypic calcium-independent cell adhesion molecule. The antigen is being used as a target for immunotherapy treatment of human carcinomas. Mutations in this gene result in congenital tufting enteropathy. [provided by RefSeq, Dec 2008]
Synonyms: EGP2 Antibody , EPCAM Antibody , M4S1 Antibody , EGP314 Antibody , KS1/4 Antibody , MK1 Antibody , MIC18 Antibody , DIAR5 Antibody , EGP40 Antibody , TROP1 Antibody , ESA Antibody , TACSTD1 Antibody , HNPCC8 Antibody , KSA Antibody , epithelial cell adhesion molecule Antibody
Cellular Localization:
CAS NO: 73232-52-7
Product: Droxinostat
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant human TACSTD1 protein
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Prepared in 10mM PBS with 0.05% BSA and 0.05% azide.
Storage Instruction:
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas with the exception of adult squamous epithelium, hepatocytes and gastric epithelial cells. Ep-CAM antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. Ep-CAM antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23960070?dopt=Abstract
