Product Name: EpCAM antibody [VU-1D9] (Biotin)
Applications: FACS, IHC, IHC-P, WB
Predicted Target Size:
Positive Controls: Breast, Colon Carcinoma and Tonsil
Form Supplied: Liquid
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein G affinity purified
Full Name: epithelial cell adhesion molecule
Background: EGP40 is a 40kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on baso-lateral cell surface in most simple epithelia and a vast majority of carcinomas. Esa1 acetylates lysine residues of the histone H4 tail in S. cerevisiae. Acetylation of histones gives a specific tag for epigenetic transcription activation – acetylation of histone H4 is essential for DNA double-strand break repair. ESA1 is required for cell cycle progression, it reportedly distinguishes adenocarcinomas from pleural mesotheliomas.
Synonyms: TROP1, MK-1, CO171A, GA7332, ESA, M4S1, EpCAM, Ep-CAM, 4072, EGP40, KSA, hEGP-2, CO17-1A, MIC18, TACSTD1, 185535, hEGP2, P16422, EGP, GA733-2, MK1, DIAR5, EGP-2, EGP314, HNPCC8, KS1/4, MK 1, EGP 2, Ep CAM, hEGP 2, EGP2
Cellular Localization:
CAS NO: 379231-04-6
Product: Rotigotine (Hydrochloride)
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Small cell lung carcinoma cells
Antigen Species: Human
Species Reactivity: Human
Conjugation: Biotin
Storage Buffer: Phosphate-buffered saline, pH 7.2, containing 0.2%BSA and 0.09% sodium azide.
Storage Instruction: Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody reacts with a 40 kD cell surface glycoprotein called epithelial specific antigen (ESA). It reacts with the same molecule which is also detected by antibodies such as 17-1A, AUA1, KS1/4, Ber-EP4, 323/A3, MOC-31, GA733, HEA125 and others.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22460558?dopt=Abstract
