Product Name: EphB4 antibody [N1N2], N-term
Applications: WB
Predicted Target Size: 108 kDa (note)
Positive Controls: 293T , A431 , Jurkat , Raji
Form Supplied: Liquid
Concentration: 0.63 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: EPH receptor B4
Background: Ephrin receptors and their ligands, the ephrins, mediate numerous developmental processes, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. Ephrin receptors make up the largest subgroup of the receptor tyrosine kinase (RTK) family. The protein encoded by this gene binds to ephrin-B2 and plays an essential role in vascular development. [provided by RefSeq]
Synonyms: HTK antibody, MYK1 antibody, TYRO11 antibody, EPHB4 antibody, soluble EPHB4 variant 2 antibody, tyrosine-protein kinase TYRO11 antibody, hepatoma transmembrane kinase antibody, soluble EPHB4 variant 1 antibody, soluble EPHB4 variant 3 antibody, ephrin receptor EphB4 antibody, ephrin type-B receptor 4 antibody, tyrosine-protein kinase receptor HTK antibody, EPH receptor B4 antibody
Cellular Localization: Membrane; Single-pass type I membrane protein
CAS NO: 143664-11-3
Product: SNS-314
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the N-terminus region of human Eph receptor B4. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16522647?dopt=Abstract
