Product Name: Ephrin A2 (cleaved Asn188) antibody
Applications: ELISA, WB
Predicted Target Size: 21 kDa (note)
Positive Controls:
Form Supplied:
Concentration:
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Full Name: ephrin-A2
Background: This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm. [provided by RefSeq]
Synonyms: HEK7L, ELF1, EFNA2, LERK6, EPLG6, EFNA2 (cleaved N188), EFNA2 (cleaved Asn188), EFNA2 cleaved N188, EFNA2 cleaved Asn188, Cleaved EFNA2 (N188), Cleaved EFNA2 (Asn188)
Cellular Localization:
CAS NO: 1032350-13-2
Product: Roscovitine
Host: Rabbit
Clonality: Polyclonal
Isotype:
Immunogen: The antiserum was produced against synthesized peptide derived from human EFNA2.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction: Store at -20 degrees Celcius. Product is stable for at least 1 year.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: EFNA2 (Cleaved-Asn188) Antibody detects endogenous levels of fragment of activated EFNA2 resulting from cleavage adjacent to Asn188.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/16006560?dopt=Abstract
