Product Name: Ephrin B3 antibody [12X1]
Applications: WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The IgG fraction of culture supernatant was purified by Protein G affinity chromatography
Full Name: ephrin-B3
Background: EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. Moreover, since levels of EFNB3 expression were particularly high in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. EPH Receptors typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin ligands and receptors have been named by the Eph Nomenclature Committee (1997). Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of recept
Synonyms: EPLG8 Antibody , EFNB3 Antibody , LERK8 Antibody , ephrin-B3 Antibody , EFL6 Antibody
Cellular Localization:
CAS NO: 1360614-48-7
Product: ARRY-380 (analog )
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2
Immunogen: Human recombinant Ephrin-B3 EC domain
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody was selected for its ability to detect human Ephrin B5.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25339738?dopt=Abstract
