Product Name: ITM2C antibody
Applications: IHC-P, WB
Predicted Target Size: 30 kDa (note) (5)
Positive Controls: HeLa
Form Supplied: Liquid
Concentration: 0.7 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: integral membrane protein 2C
Background: Negative regulator of beta amyloid peptide production. May inhibit the processing of APP by blocking its access to alpha-and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation.
Synonyms: BRI3 antibody, BRICD2C antibody, E25 antibody, E25C antibody, ITM3 antibody, ITM2C antibody, BRICHOS domain containing 2C antibody, integral membrane protein 3 antibody, transmembrane protein BRI3 antibody, hRPC.1050_D_4 antibody, integral membrane protein 2C antibody, cerebral protein 14 antibody
Cellular Localization: Membrane; Single-pass type II membrane protein
CAS NO: 54447-84-6
Product: Benfluorex (hydrochloride)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human ITM2C. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21143673?dopt=Abstract
