Product Name: IVNS1ABP antibody
Applications: IHC-P, WB
Predicted Target Size: 72 kDa (note) (2)
Positive Controls: NT2D1 , IMR32 , U87-MG , MCF-7
Form Supplied: Liquid
Concentration: 0.57 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: influenza virus NS1A binding protein
Background: Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.
Synonyms: DKFZp686K06216 antibody, FLARA3 antibody, FLJ10069 antibody, FLJ10411 antibody, FLJ10962 antibody, FLJ35593 antibody, FLJ36593 antibody, HSPC068 antibody, KIAA0850 antibody, KLHL39 antibody, ND1 antibody, NS-1 antibody, NS1-BP antibody, NS1BP antibody, IVNS1ABP antibody, aryl hydrocarbon receptor-associated 3 antibody, influenza virus NS1A-binding protein antibody, NS1-binding protein antibody, aryl hydrocarbon receptor-associated protein 3 antibody, NCX downstream gene 1 antibody, influenza virus NS1A binding protein antibody
Cellular Localization: Cytoplasm , cytoskeleton , Nucleus , nucleoplasm
CAS NO: 163269-30-5
Product: Ethylenediaminetetraacetic acid (trisodium salt)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human IVNS1ABP. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19570034?dopt=Abstract
