Product Name: JAM-A antibody, C-term
Applications: WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: F11 receptor
Background: Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus.
Synonyms: F11R / JAMA, JAM-A, PAM-1, F11 receptor, OTTHUMP00000027881, JAMA, platelet adhesion molecule, platelet F11 receptor, CD321, JAM, OTTHUMP00000027880, junctional adhesion, JAM1, junctional adhesion molecule A, JAM-1, PAM1, JCAM, KAT, F11R, JAM A, PAM 1, JAM 1
Cellular Localization: Localized at tight junctions of both epithelial and endothelial cells.
CAS NO: 828934-41-4
Product: Medrysone
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: C-QPSARSEGEFKQTS
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for JAM-A.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/15905578?dopt=Abstract
