Product Name: JAM-B antibody [N2C3]
Applications: WB
Predicted Target Size: 33 kDa (note) (4)
Positive Controls: THP-1
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: junctional adhesion molecule 2
Background: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. The protein encoded by this immunoglobulin superfamily gene member is localized in the tight junctions between high endothelial cells. It acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs. [provided by RefSeq]
Synonyms: C21orf43 antibody, CD322 antibody, JAM-B antibody, JAMB antibody, PRO245 antibody, VE-JAM antibody, VEJAM antibody, JAM2 antibody, JAM-IT/VE-JAM antibody, JAM-2 antibody, junctional adhesion molecule B antibody, vascular endothelial junction-associated molecule antibody, junctional adhesion molecule 2 antibody
Cellular Localization: Cell junction , tight junction (By similarity) , Cell membrane; Single-pass type I membrane protein (By similarity)
CAS NO: 1403783-31-2
Product: Phenothrin
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human JAM-B. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/15339660?dopt=Abstract
