Product Name: JIP2 antibody [C1C3]
Applications: ICC/IF, WB
Predicted Target Size: 88 kDa (note) (2)
Positive Controls: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji , mouse brain
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: mitogen-activated protein kinase 8 interacting protein 2
Background: The protein encoded by this gene is closely related to MAPK8IP1/IB1/JIP-1, a scaffold protein that is involved in the c-Jun amino-terminal kinase signaling pathway. This protein is expressed in brain and pancreatic cells. It has been shown to interact with, and regulate the activity of MAPK8/JNK1, and MAP2K7/MKK7 kinases. This protein thus is thought to function as a regulator of signal transduction by protein kinase cascade in brain and pancreatic beta-cells. Alternatively spliced transcript variants encoding distinct isoforms have been reported for this gene. [provided by RefSeq]
Synonyms: IB2 antibody, JIP2 antibody, PRKM8IPL antibody, MAPK8IP2 antibody, C-Jun-amino-terminal kinase-interacting protein 2 antibody, homologous to mouse JIP-1 antibody, IB-2 antibody, JNK MAP kinase scaffold protein JIP2 antibody, JNK MAP kinase scaffold protein 2 antibody, islet-brain 2 antibody, JNK-interacting protein 2 antibody, JIP-2 antibody, mitogen-activated protein kinase 8-interacting protein 2 antibody, islet-brain-2 antibody, mitogen-activated protein kinase 8 interacting protein 2 antibody
Cellular Localization: Cytoplasm
CAS NO: 873857-62-6
Product: 4-Aminobenzoic acid
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human JIP2. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26201611?dopt=Abstract
