Product Name: Jab1 antibody [8H8.5]
Applications: IP, WB
Predicted Target Size: 38 kDa (note)
Positive Controls: 293 cell lysate
Form Supplied: Liquid
Concentration: Batch dependent (Please refer to the vial label for the specific concentration)
Purification: Protein G purified
Full Name: COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
Background: JAB-1 is a 38a protein which was originally described as a coactivator for cJUN. It is present in a large protein complex called the “”Signalosome””, which has been proposed to play a signaling role in mammalian cells. This protein complex appears to be analogous to the COP9 complex in plants, which is important in light-mediated plant development. Although the specific function of JAB-1 in this complex is unclear, it has recently been implicated in targeting proteins for degradation by the proteasome.
Synonyms: Jab 1 Jab-1 Jab1 JabI
Cellular Localization: Nuclear/Cytoplasmic
CAS NO: 328898-40-4
Product: Lappaconitine (hydrobromide)
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2a
Immunogen: The full-length mouse JAB-1 gene expressed in E. coli.
Antigen Species: Mouse
Species Reactivity: Human, Mouse, Drosophila
Conjugation: Unconjugated
Storage Buffer: Phosphate-buffered saline, pH 7.4, containing no preservatives
Storage Instruction: Keep as concentrated solution. Store at 4°C short term. For extended storage aliquot and store at -20°C or below. Avoid freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19828458?dopt=Abstract
