Product Name: Jab1 antibody [N1C1]
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 38 kDa (note) (2)
Positive Controls: HeLa , mouse brain
Form Supplied: Liquid
Concentration: 0.35 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis)
Background: The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. The structure and function of COP9 signalosome is similar to that of the 19S regulatory particle of 26S proteasome. COP9 signalosome has been shown to interact with SCF-type E3 ubiquitin ligases and act as a positive regulator of E3 ubiquitin ligases. This protein is reported to be involved in the degradation of cyclin-dependent kinase inhibitor CDKN1B/p27Kip1. It is also known to be an coactivator that increases the specificity of JUN/AP1 transcription factors. [provided by RefSeq]
Synonyms: CSN5 antibody, JAB1 antibody, MGC3149 antibody, MOV-34 antibody, SGN5 antibody, COPS5 antibody, jun activation domain-binding protein 1 antibody, signalosome subunit 5 antibody, 38 kDa Mov34 homolog antibody, COP9 signalosome complex subunit 5 antibody, COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis) antibody
Cellular Localization: Cytoplasm , Nucleus
CAS NO: 156722-18-8
Product: Indaconitine
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human Jab1. The exact sequence is proprietary.
Antigen Species:
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19394332?dopt=Abstract
