Product Name: Jagged 1 antibody [EPR4290]
Applications: IHC-Fr, IHC-P, WB
Predicted Target Size: 134 kDa (note)
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Protein A purified
Full Name: jagged 1
Background: Jagged 1 is the human homolog of the Drosophilia jagged protein. Human jagged 1 is the ligand for the receptor notch 1, the latter a human homolog of the Drosophilia jagged receptor notch. Mutations that alter the Jagged 1 protein cause Alagille syndrome. Jagged 1 signaling through notch 1 has also been shown to play a role in hematopoiesis (1).
Synonyms: AGS, AHD, AWS, HJ1, JAGL1, MGC104644
Cellular Localization:
CAS NO: 283159-90-0
Product: Betamipron
Host: Rabbit
Clonality: Monoclonal
Isotype: IgG
Immunogen: A synthetic peptide corresponding to residues near the C-terminus of human Jagged 1 was used as an immunogen.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
Storage Instruction: Store at -20 °C. Stable for 12 months from date of receipt.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption. RabMAb® technology is covered by the following U.S. Patents, No. 5,675,063 and/or 7,429,488.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18272684?dopt=Abstract
