Product Name: KAP1 antibody, C-term
Applications: ICC/IF, IHC-P, WB, ChIP assay
Predicted Target Size:
Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX89879-PEP).
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: tripartite motif containing 28
Background: Forms a complex with a KRAB-domain transcription factor and increases the efficiency of KRAB-mediated repression. Silences transcription through an interaction with HP1 proteins. Acts as a corepressor of transcription for the KRAB zinc finger proteins and as a moderator of the repression activity. May play a role as a coactivator for CEBPB and NR3C1 in the transcriptional activation of the Alpha-1-acid glycoprotein gene.
Synonyms: KRABassociated protein1, KRABassociated protein 1, tripartite motifcontaining28 protein, transcriptional intermediary factor1beta, tripartite motifcontaining28, transcriptional intermediary factor 1beta, tripartite motifcontaining 28 protein, nuclear corepressor KAP1, KRAB-associated protein 1, tripartite motifcontaining 28, TF1B, transcriptional intermediary factor1be, transcriptional intermediary factor 1-be, nuclear corepressor KAP-1, KAP1 / TRIM28, TRIM28, FLJ29029, KAP1, RNF96, TIF1B, KRAB associated protein 1, nuclear corepressor KAP 1
Cellular Localization: Associated with centromeric heterochromatin during cell differentiation through CBX1.
CAS NO: 1375603-36-3
Product: Pidotimod
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: C-SSQELSGGPGDGP
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for KAP1 / TRIM28.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26430725?dopt=Abstract
