Product Name: KCC4 antibody [C2C3], C-term
Applications: WB
Predicted Target Size: 119 kDa (note)
Positive Controls: A431 , H1299 , HepG2 , Raji
Form Supplied: Liquid
Concentration: 4.71 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified by Protein A.
Full Name: solute carrier family 12 (potassium/chloride transporters), member 7
Background: Mediates electroneutral potassium-chloride cotransport when activated by cell swelling. May mediate K(+) uptake into Deiters cells in the cochlea and contribute to K(+) recycling in the inner ear. Important for the survival of cochlear outer and inner hair cells and the maintenance of the organ of Corti. May be required for basolateral Cl(-) extrusion in the kidney and contribute to renal acidification.
Synonyms: DKFZp434F076 antibody, KCC4 antibody, SLC12A7 antibody, potassium/chloride transporter KCC4 antibody, electroneutral potassium-chloride cotransporter 4 antibody, K-Cl cotransporter 4 antibody, solute carrier family 12 member 7 antibody, “solute carrier family 12 (potassium/chloride transporters), member 7 antibody”
Cellular Localization: Membrane; Multi-pass membrane protein
CAS NO: 37025-55-1
Product: Diatrizoic acid
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human KCC4. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25680807?dopt=Abstract