Product Name: KCNE3 antibody
Applications: ICC/IF, IHC, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Affinity purified on immobilized antigen.
Full Name: potassium voltage-gated channel, Isk-related family, member 3
Background: Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, isk-related subfamily. This member is a type I membrane protein, and a beta subunit that assembles with a potassium channel alpha-subunit to modulate the gating kinetics and enhance stability of the multimeric complex. This gene is prominently expressed in the kidney. A missense mutation in this gene is associated with hypokalemic periodic paralysis. [provided by RefSeq, Jul 2008]
Synonyms: MiRP2 Antibody , HYPP Antibody , potassium voltage-gated channel, Isk-related family, member 3 Antibody , HOKPP Antibody
Cellular Localization:
CAS NO: 1374828-69-9
Product: Alisol A (24-acetate)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Peptide (C)RSRKVDKRSDPYH, corresponding to amino acid residues 81-93 of human KCNE3 (Accession Q9Y6H6 ). Intracellular, C-terminal part.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: Phosphate buffered saline (PBS), pH 7.4, 1% BSA, 0.025% NaN3.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24586582?dopt=Abstract