Product Name: KCNJ1 / ROMK antibody, Internal
Applications: WB
Predicted Target Size: 44.8; 42.7 (note)
Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX47558-PEP).
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: potassium inwardly-rectifying channel, subfamily J, member 1
Background: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. It is activated by internal ATP and probably plays an important role in potassium homeostasis. The encoded protein has a greater tendency to allow potassium to flow into a cell rather than out of a cell. Mutations in this gene have been associated with antenatal Bartter syndrome, which is characterized by salt wasting, hypokalemic alkalosis, hypercalciuria, and low blood pressure. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]
Synonyms: ATPsensitive inward rectifier potassium channel1, ATP-regulated potassium channel ROM-K, potassium inwardlyrectifying channel J1, inwardly recti, ATPsensitive inward rectifier potassium channel 1, ATPregulated potassium channel ROMK, ATP-sensitive inward rectifier potassium channel 1, potassium inwardly-rectifying channel J1, KCNJ1 / ROMK
Cellular Localization:
CAS NO: 9041-93-4
Product: Bromperidol
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: C-DQININFVVDAGNEN
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for KCNJ1 / ROMK.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24074531?dopt=Abstract
