Product Name: KCNN2 antibody, C-term
Applications: IHC-P, WB
Predicted Target Size: 64 KDa (note)
Positive Controls: HepG2 , human fetal liver
Form Supplied: Lyophilized powder
Concentration: 0.5-1 mg/ml
Purification: Protein A purified
Full Name: potassium calcium-activated channel subfamily N member 2
Background: Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. The protein encoded by this gene is activated before membrane hyperpolarization and is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene is a member of the KCNN family of potassium channel genes. The encoded protein is an integral membrane protein that forms a voltage-independent calcium-activated channel with three other calmodulin-binding subunits. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, May 2013]
Synonyms: SKCA2 Antibody , KCNN2 Antibody , SK2 Antibody , HSK2 Antibody , KCA2.2 Antibody
Cellular Localization:
CAS NO: 69-78-3
Product: 4-Nonylphenol polyethoxylate
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: A synthetic peptide corresponding to a C-terminal region of Human KCNN2.
Antigen Species: Human
Species Reactivity: Human, Rat, Rhesus Monkey
Conjugation: Unconjugated
Storage Buffer: 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25995248?dopt=Abstract
