Product Name: KCNQ1 antibody [5E12]
Applications: ELISA, FACS, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Unpurified
Full Name: potassium voltage-gated channel subfamily Q member 1
Background: This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2011]
Synonyms: LQT1 Antibody , KVLQT1 Antibody , WRS Antibody , RWS Antibody , ATFB3 Antibody , JLNS1 Antibody , SQT2 Antibody , KV7.1 Antibody , ATFB1 Antibody , KCNA8 Antibody , KCNA9 Antibody , LQT Antibody , KV1.9 Antibody
Cellular Localization:
CAS NO: 1708766
Product: Suramin
Host: Mouse
Clonality: Monoclonal
Isotype: IgG2b
Immunogen: Purified recombinant fragment of human KCNQ1 expressed in E. Coli.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Ascites, 0.03% sodium azide
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24469828?dopt=Abstract
