Product Name: KCNQ1 antibody [S37A-10]
Applications: IHC, IP, WB
Predicted Target Size: 75kDa (note)
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein G Purified
Full Name: potassium voltage-gated channel, KQT-like subfamily, member 1
Background: This gene encodes a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome, Romano-Ward syndrome, Jervell and Lange-Nielsen syndrome and familial atrial fibrillation. The gene is located in a region of chromosome 11 that contains a large number of contiguous genes that are abnormally imprinted in cancer and the Beckwith-Wiedemann syndrome. Two alternative transcripts encoding distinct isoforms have been described. [provided by RefSeq]
Synonyms: JLNS1, ATFB1, LQT, Kv1.9, RWS, Kv7.1, KCNQ1, voltage gated potassium channel subunit KV7.1, SQT2, KCNA8, KVLQT1, KCNA9, LQT1
Cellular Localization:
CAS NO: 979-88-4
Product: Milbemycin oxime
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Fusion protein amino acids 2-101 of human KCNQ1, accession number P51787
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: PBS pH7.4, 50% glycerol
Storage Instruction: Aliquot and store at -20 C. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24591630?dopt=Abstract