Product Name: KCNQ5 antibody [N3C2], Internal
Applications: WB
Predicted Target Size: 102 kDa (note) (4)
Positive Controls: 293T , A431 , H1299 , HeLaS3
Form Supplied: Liquid
Concentration: 0.45 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: potassium voltage-gated channel, KQT-like subfamily, member 5
Background: This gene is a member of the KCNQ potassium channel gene family that is differentially expressed in subregions of the brain and in skeletal muscle. The protein encoded by this gene yields currents that activate slowly with depolarization and can form heteromeric channels with the protein encoded by the KCNQ3 gene. Currents expressed from this protein have voltage dependences and inhibitor sensitivities in common with M-currents. They are also inhibited by M1 muscarinic receptor activation. Three alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the full-length nature of only one has been determined. [provided by RefSeq]
Synonyms: Kv7.5 antibody, KCNQ5 antibody, potassium channel protein antibody, voltage-gated potassium channel subunit Kv7.5 antibody, potassium channel subunit alpha KvLQT5 antibody, potassium voltage-gated channel subfamily KQT member 5 antibody, KQT-like 5 antibody, “potassium voltage-gated channel, KQT-like subfamily, member 5 antibody”
Cellular Localization: Membrane; Multi-pass membrane protein
CAS NO: 82611-88-9
Product: Mexiletine (hydrochloride)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human KCNQ5. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23709690?dopt=Abstract
