Product Name: KCTD15 antibody [AT4C3]
Applications: ELISA, ICC/IF, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: By protein-G affinity chromatography
Full Name: potassium channel tetramerisation domain containing 15
Background: KCTD15 (Potassium channel tetramerisation domain containing 15, also known as BTB/POZ domain-containing protein KCTD15) is protein that in humans is encoded by the KCTD15 gene. KCTD15 is expressed at high level in brain and hypothalamus. The potassium channel KCTD15 was identified as a genetic loci associated with higher than normal body mass index (BMI) in humans along with genes such as GNPDA2, MTCH2, FTO, and TMEM18. Single nucleotide polymorphisms (SNPs) in non-diabetic and diabetic patients showed that FTO was most strongly associated with obesity while MTCH2 and GNPDA2 were still significantly associated with higher than normal BMI levels.
Synonyms: MGC2628, BTB/POZ domain-containing protein KCTD15, potassium channel tetramerisation domain containing15, MGC25497, potassium channel tetramerisation domain containing 15, BTB/POZ domaincontaining protein KCTD15
Cellular Localization:
CAS NO: 382-67-2
Product: AMG-47a
Host: Mouse
Clonality: Monoclonal
Isotype: IgG3
Immunogen: Recombinant human KCTD15 (1-234) purified from E.coli
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: In Phosphate-Buffered Saline (pH 7.4) with 0.1% Sodium Azide
Storage Instruction: Can be stored at +4C. For long term storage, aliquot and store at -20C. Avoid repeated freezing and thawing cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21576363?dopt=Abstract
