Product Name: KIF17 antibody
Applications: ICC/IF, WB
Predicted Target Size:
Positive Controls: mouse brain cytosolic fraction, PC12, NGF
Form Supplied: Liquid
Concentration:
Purification: Purified by affinity chromatography
Full Name: kinesin family member 17
Background: The kinesin superfamily of proteins (KIFs) consists of a class of microtubule-dependent motors that play a major role in many cellular and developmental functions, including organelle transport, mitosis, meiosis, and possibly long-range signaling in neurons. The kinesin proteins are involved in organelle transport and are primarily associated with anterograde transport of vesicles and organelles in neurons, epithelial cells, and melanosomes with bidirectional transport of mitochondria. They also mediate transport between the endoplasmic reticulum (ER) and the Golgi complex. In neurons, kinesin motors conduct vesicular transport, such as of synaptic vesicle components to axons and of neurotransmitter receptors to dendrites. KIF17 belongs to the functionally diverse subgroup of the kinesin superfamily characterized by a N-terminal motor domain (N-IV class), that includes the KIF3 motor protein. KIF17 is specifically expressed in the brain, present in abundance in the gray matter, particularly in the hippocampus and cerebral cortex, but not in the white matter such as the optic nerve.
Synonyms: 5930435E01Rik, AW492270, Kif17b, mKIAA1405
Cellular Localization:
CAS NO: 83480-29-9
Product: Dehydroandrographolide
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: synthetic peptide corresponding to amino acids 589-606 of mouse KIF17 conjugated to KLH.
Antigen Species: Mouse
Species Reactivity: Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: 0.01M PBS pH7.4, 15 mM sodium azide
Storage Instruction: Keep as concentrated solution. For short-term storage, store at 4° C (up to 10 days). For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/25329383?dopt=Abstract
