Product Name: KIF5B antibody, C-term
Applications: IHC-P, WB
Predicted Target Size:
Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX15705-PEP).
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: kinesin family member 5B
Background: KIF5B is a kinesin. These are microtubule based motor proteins involved in the transport of organelles in eukaryotic cells. They typically consist of 2 identical, approximately 110 to 120 kD heavy chains and 2 identical, approximately 60 to 70 kD light chains. The heavy chain contains 3 domains: a globular N terminal motor domain, which converts the chemical energy of ATP into a motile force along microtubules in 1 fixed direction; a central alpha helical rod domain, which enables the 2 heavy chains to dimerize; and a globular C terminal domain, which interacts with light chains and possibly an organelle receptor.
Synonyms: KINH, Kinesin1 / UKHC, kinesin family member5B, kinesin1 (110120kD), U-KHC, KNS, kinesin 1 (110120kD), KIF5B, UKHC, kinesin family member 5B, Kinesin 1 / UKHC, kinesin 1 (110-120kD), KNS1, kinesin heavy chain, U KHC
Cellular Localization: Uniformly distributed between the cell body and the processes in the neurons.
CAS NO: 594839-88-0
Product: Scopine (hydrochloride)
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: C-QPVAVRGGGGKQV
Antigen Species: Human
Species Reactivity: Human, Dog
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for KIF5B.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/21965290?dopt=Abstract
