Product Name: KLB antibody [N1N3]
Applications: WB
Predicted Target Size: 120 kDa (note)
Positive Controls: *3T3-L1 cells
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: klotho beta
Background: Contributes to the transcriptional repression of cholesterol 7-alpha-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis. Probably inactive as a glycosidase. Increases the ability of FGFR1 and FGFR4 to bind FGF21.
Synonyms: BKL antibody, MGC142213 antibody, KLB antibody, beta-klotho antibody, klotho beta-like protein antibody, betaKlotho antibody, klotho beta like antibody, klotho beta antibody
Cellular Localization: Cell membrane; Single-pass type III membrane protein
CAS NO: 850-52-2
Product: Itraconazole metabolite Hydroxy Itraconazole
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human KLB. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Mouse
Conjugation: Unconjugated
Storage Buffer: 1XPBS, 1% BSA, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20oC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/24298057?dopt=Abstract
