Product Name: KLC1 antibody
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 65 kDa (note)
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: Affinity purification
Full Name: kinesin light chain 1
Background: Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named “kinesin 2”, this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature and/or biological validity of most of these variants have not been determined. [prov
Synonyms: KNS2 Antibody , kinesin light chain 1 Antibody , KNS2A Antibody , KLC Antibody
Cellular Localization:
CAS NO: 132-17-2
Product: Mebeverine metabolite Mebeverine alcohol
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein of human KLC1
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage Instruction: Store at -20°C (regular) or -80°C (long term). Avoid freeze / thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/22279212?dopt=Abstract
