Product Name: KPNA4 antibody, C-term
Applications: IHC-P, WB
Predicted Target Size:
Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX26039-PEP).
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: karyopherin alpha 4 (importin alpha 3)
Background: The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.
Synonyms: karyopherin alpha 4, KPNA4 / IPOA3, karyopherin alpha4, importin alpha3, karyopherin alpha 4 (importin alpha 3), importin alpha 3, karyopherin alpha4 (importin alpha3), importin-alpha-Q1, MGC12217, MGC26703, SRP3, importinalphaQ1, IPOA3, QIP1, KPNA4, importin alpha Q1
Cellular Localization: Cytoplasmic and Nuclear
CAS NO: 7081-53-0
Product: PNRI-299
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: C-NSSANVPTEGFQF
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for KPNA4.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19318571?dopt=Abstract
