Product Name: KREMEN2 antibody
Applications: ELISA, ICC/IF, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity chromatography purified via peptide column.
Full Name: kringle containing transmembrane protein 2
Background: This gene encodes a high-affinity dickkopf homolog 1 (DKK1) transmembrane receptor. A similar protein in mouse functions interacts with with DKK1 to block wingless (WNT)/beta-catenin signaling. The encoded protein forms a ternary membrane complex with DKK1 and the WNT receptor lipoprotein receptor-related protein 6 (LRP6), and induces rapid endocytosis and removal of LRP6 from the plasma membrane. It contains extracellular kringle, WSC, and CUB domains. Alternatively spliced transcript variants encoding distinct isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Synonyms: kringle containing transmembrane protein 2 Antibody , KRM2 Antibody
Cellular Localization:
CAS NO: 75530-68-6
Product: LY2409881 (trihydrochloride)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: KREMEN2 antibody was raised against a 15 amino acid peptide near the carboxy terminus of human KREMEN2 .
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: PBS containing 0.02% sodium azide.
Storage Instruction: Be stored at 4oC for three months and -20oC, stable for up to one year.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Multiple isoforms of KREMEN2 are known to exist. KREMEN2 antibody is predicted to not cross-react with other Kremen protein family members.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/18567746?dopt=Abstract
