Product Name: Kalirin (isoform 2) antibody, C-term
Applications: IHC, WB
Predicted Target Size:
Positive Controls: The peptide used to product this antibody is available for purchase (Catalog Number:GTX89287-PEP).
Form Supplied: Liquid
Concentration: 0.5 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Full Name: kalirin, RhoGEF kinase
Background: Promotes the exchange of GDP by GTP. Activates specific Rho GTPase family members, thereby inducing various signaling mechanisms that regulate neuronal shape, growth, and plasticity, through their effects on the actin cytoskeleton. Induces lamellipodia independent of its GEF activity.
Synonyms: serine/threonine kinase with Dbl- and pleckstrin homology d, DUET, huntingtinassociated protein interacting protein (duo), serine/threonine kinase with Dbl and pleckstrin homology d, huntingtin-associated protein interacting protein (duo), kalirin, RhoGEF kinase, DUO, FLJ12332, FLJ18623, KALRN, hCG2022551, Kalirin (isoform2), ARHGEF24, FLJ16443, FLJ18196, HAPIP, TRAD
Cellular Localization: Associated with the cytoskeleton.
CAS NO: 857652-30-3
Product: Dioxybenzone
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Immunogen: C-RWHLGPGDPFSTYV
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Storage Instruction: Aliquot and store at -20°C. Minimize freezing and thawing.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: This antibody is specific for Kalirin (isoform 2).
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20413689?dopt=Abstract
