Product Name: Kallikrein 6 antibody
Applications: ICC/IF
Predicted Target Size: 27 kDa (note)
Positive Controls: Target recombinant protein
Form Supplied: Liquid
Concentration: 0.88 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: kallikrein-related peptidase 6
Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. The encoded enzyme is regulated by steroid hormones. In tissue culture, the enzyme has been found to generate amyloidogenic fragments from the amyloid precursor protein, suggesting a potential for involvement in Alzheimers disease. Multiple alternatively spliced transcript variants that encode different isoforms have been identified for this gene. [provided by RefSeq]
Synonyms: Bssp antibody, Klk7 antibody, MGC9355 antibody, PRSS18 antibody, PRSS9 antibody, SP59 antibody, hK6 antibody, KLK6 antibody, serine protease 9 antibody, kallikrein-6 antibody, neurosin antibody, protease M antibody, serine protease 18 antibody, zyme antibody, kallikrein-related peptidase 6 antibody
Cellular Localization: Secreted , Nucleus , nucleolus , Cytoplasm , Mitochondrion , Microsome
CAS NO: 375345-95-2
Product: Hydroxysafflor yellow A
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the center region of human Kallikrein 6. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27469333?dopt=Abstract