Product Name: Kallikrein 8 (cleaved Val33) antibody
Applications: ELISA, WB
Predicted Target Size: 24 kDa (note)
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Full Name: kallikrein-related peptidase 8
Background: Serine protease which is capable of degrading a number of proteins such as casein, fibrinogen, kininogen, fibronectin and collagen type IV. Also cleaves L1CAM in response to increased neural activity. Induces neurite outgrowth and fasciculation of cultured hippocampal neurons. Plays a role in the formation and maturation of orphan and small synaptic boutons in the Schaffer-collateral pathway, regulates Schaffer-collateral long-term potentiation in the hippocampus and is required for memory acquisition and synaptic plasticity. Involved in skin desquamation and keratinocyte proliferation. Plays a role in the secondary phase of pathogenesis following spinal cord injury.
Synonyms: HNP, TADG14, NRPN, Neuropsin, NP, PRSS19, Neuropsin (cleaved V33), Neuropsin (cleaved Val33), Neuropsin cleaved V33, Neuropsin cleaved Val33, Cleaved Neuropsin (V33), Cleaved Neuropsin (Val33)
Cellular Localization: Shows a cytoplasmic distribution in the keratinocytes.
CAS NO: 142217-69-4
Product: Riboflavin (phosphate sodium)
Host: Rabbit
Clonality: Polyclonal
Isotype:
Immunogen:
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Instruction: Store at -20 degrees Celcius. Product is stable for at least 1 year.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Kallikrein 8 (Cleaved-Val33) Antibody detects endogenous levels of fragment of activated Neuropsin resulting from cleavage adjacent to Val33.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/27622920?dopt=Abstract
