Product Name: Kinectin 1A antibody [C2C3], C-term
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 156 kDa (note) (4)
Positive Controls: 293T , A431 , H1299 , HeLa , HepG2 , Molt-4 , Raji
Form Supplied: Liquid
Concentration: 0.34 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: kinectin 1 (kinesin receptor)
Background: Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm. Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes. The transport of organelles requires a special class of microtubule-associated proteins (MAPs). One of these is the molecular motor kinesin (see MIM 148760 and MIM 600025), an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule. Another such MAP is kinectin, a large integral ER membrane protein. Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.[supplied by OMIM]
Synonyms: CG1 antibody, KIAA0004 antibody, KNT antibody, MGC133337 antibody, MU-RMS-40.19 antibody, KTN1 antibody, CG-1 antigen antibody, kinesin receptor antibody, kinectin antibody, kinectin 1 (kinesin receptor) antibody
Cellular Localization: Endoplasmic reticulum membrane; Single-pass type II membrane protein
CAS NO: 72558-82-8
Product: PF 05089771
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human Kinectin 1A. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human, Mouse
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/19321499?dopt=Abstract
