Product Name: Kir2.1 antibody [S112B-14]
Applications: ICC/IF, IHC-P, WB
Predicted Target Size: 45kDa (note)
Positive Controls:
Form Supplied: Liquid
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Protein G purified
Full Name: potassium inwardly-rectifying channel, subfamily J, member 2
Background: Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium.
Synonyms: IRK1, HIRK1, HHBIRK1, KCNJ2, SQT3, HIRK 1, HHIRK1, LQT7, potassium inwardly rectifying channel J2
Cellular Localization:
CAS NO: 441045-17-6
Product: Optovin
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Fusion protein amino acids 41-64 and 189-428 of mouse Kir2.1, accession number NP_032451.
Antigen Species: Mouse
Species Reactivity: Human, Mouse, Rat
Conjugation: Unconjugated
Storage Buffer: PBS pH7.4, 50% glycerol
Storage Instruction: Aliquot and store at -20 C. Avoid repeated freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: No cross-reactivity against Kir2.2 or Kir2.3
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26229551?dopt=Abstract
