Product Name: Kiss1 antibody
Applications: ELISA, IHC-P, WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration: 0.50 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Affinity purified
Full Name: KiSS-1 metastasis-suppressor
Background: This gene is a metastasis suppressor gene that suppresses metastases of melanomas and breast carcinomas without affecting tumorigenicity. The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas. Studies suggest a putative role in the regulation of events downstream of cell-matrix adhesion, perhaps involving cytoskeletal reorganization. A protein product of this gene, kisspeptin, stimulates gonadotropin-releasing hormone (GnRH)-induced gonadotropin secretion and regulates the pubertal activation of GnRH nuerons. A polymorphism in the terminal exon of this mRNA results in two protein isoforms. An adenosine present at the polymorphic site represents the third position in a stop codon. When the adenosine is absent, a downstream stop codon is utilized and the encoded protein extends for an additional seven amino acid residues. [provided by RefSeq, Mar 2012]
Synonyms: KiSS-1 metastasis-suppressor Antibody , KiSS-1 Antibody , HH13 Antibody , KISS1 Antibody
Cellular Localization:
CAS NO: 69-52-3
Product: Ivabradine metabolite N-Demethyl Ivabradine (hydrochloride)
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: The immunogen sequence falls between 81-138 AA of human KISS1.
Antigen Species: Human
Species Reactivity: Human, Mouse, Rat, Sheep, Bovine, Sheep
Conjugation: Unconjugated
Storage Buffer: 10 mM PBS, pH 7.4 with 10 mg/ml BSA and 0.1% sodium azide
Storage Instruction: Store at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/23965993?dopt=Abstract
