Product Name: Klotho antibody [N3], Internal
Applications: ELISA-Ag
Predicted Target Size: 116 kDa (note)
Positive Controls: Synthetic peptide: 1:8,000
Form Supplied: Liquid
Concentration: 0.96 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by antigen-affinity chromatography.
Full Name: klotho
Background: This gene encodes a type-I membrane protein that is related to beta-glucosidases. Reduced production of this protein has been observed in patients with chronic renal failure (CRF), and this may be one of the factors underlying the degenerative processes (e.g., arteriosclerosis, osteoporosis, and skin atrophy) seen in CRF. Also, mutations within this protein have been associated with ageing and bone loss. [provided by RefSeq]
Synonyms: KL antibody, klotho antibody
Cellular Localization: Isoform 1: Cell membrane; Single-pass type I membrane protein , Isoform 2: Secreted , Klotho peptide: Secreted
CAS NO: 61-68-7
Product: Schisandrin C
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Klotho. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity:
Conjugation: Unconjugated
Storage Buffer: 0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Storage Instruction: Keep as concentrated solution. Aliquot and store at -20ÂșC or below. Avoid multiple freeze-thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/20580947?dopt=Abstract
