Product Name: Ku70 (Acetyl Lys542) antibody
Applications: WB
Predicted Target Size:
Positive Controls:
Form Supplied: Liquid
Concentration:
Purification: The antibody was purified by immunogen affinity chromatography.
Full Name: X-ray repair complementing defective repair in Chinese hamster cells 6
Background: The p70/p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single-stranded DNA-dependent ATP-dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double-strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with systemic lupus erythematosus. [provided by RefSeq, Jul 2008]
Synonyms: X-ray repair complementing defective repair in Chinese hamster cells 6 Antibody , G22P1 Antibody , TLAA Antibody , CTCBF Antibody , ML8 Antibody , KU70 Antibody , XRCC6 Antibody , CTC75 Antibody
Cellular Localization:
CAS NO: 140462-76-6
Product: SR1001
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the C-term region of human Ku70. The exact sequence is proprietary.
Antigen Species: Human
Species Reactivity: Human
Conjugation: Unconjugated
Storage Buffer: Liquid in 0.42% Potassium phosphate; 0.87% Sodium chloride; pH 7.3; 30% glycerol; and 0.01% sodium azide.
Storage Instruction: Shipped at 4 °C. Upon delivery aliquot and store at -20 °C for one year. Avoid freeze/thaw cycles.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity: Recognizes endogenous levels of Ku70 (AcK542) protein.
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/17091399?dopt=Abstract
