Product Name: Ku80 antibody [111]
Applications: FACS, ICC/IF, IP, WB
Predicted Target Size:
Positive Controls: HeLa or BT474 cells
Form Supplied: Liquid
Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration)
Purification: Purified by ammonium sulfate precipitation.
Full Name: X-ray repair complementing defective repair in Chinese hamster cells 5 (double-strand-break rejoining)
Background: The Ku autoantigen is a heterodimer of 70 kDa (p70) and ~80 kDa (p80) proteins. The p70 / p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase that phosphorylates certain transcription factors, including Sp1, Oct-1, p53, and SV40 large T antigen in vitro. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.
Synonyms: FLJ39089, KARP-1, KARP1, KU80, KUB2, Ku86, NFIV, KARP 1
Cellular Localization: Nuclear
CAS NO: 34552-83-5
Product: SCR7
Host: Mouse
Clonality: Monoclonal
Isotype: IgG1
Immunogen: Human B cell nuclei from plasmacytoid 2p68 cells.
Antigen Species: Human
Species Reactivity: Human, Monkey
Conjugation: Unconjugated
Storage Buffer: 10mM Phosphate-buffered saline, pH7.4 containing 0.2% BSA and 0.09% sodium azide
Storage Instruction: Keep as concentrated solution, aliquot and store at 4°C. Do not freeze.
Notes: For In vitro laboratory use only. Not for any clinical, therapeutic, or diagnostic use in humans or animals. Not for animal or human consumption.
Specificity:
PubMed ID:http://www.ncbi.nlm.nih.gov/pubmed/26070712?dopt=Abstract
